Schiff Base Metal Chloride Complexes of Dapsone and Pyridine-2-Carboxaldehyde Their Synthesis, Characterization And Antifungal Properties

Authors

  • Monika Author
  • Arpna Author
  • Pallavi Bhardwaj Author

DOI:

https://doi.org/10.53555/AJBR.v28i1.4875

Keywords:

Dapsone, Pyridine-2-carboxaldehyde, biological properties, Schiff base, Schiff base metal complexes.

Abstract

Schiff bases have been the subject of much research due to their important bioactivities, active azomethine (-N=CH-) pharmacophore, is structurally similar to naturally occurring biological compounds, have selectivity, sensitivity and synthetic flexibility to the central metal atom [1-2].

In present paper we will synthesize Schiff base by condensing Dapsone with Pyridine -2-carboxaldehyde. Then Schiff base formed was complexed with metal ions. IR, elemental analysis, UV, M.P were used to analyse the complexes. Then evaluate their biological properties. Biological properties of metal complexes were greater than that of Dapsone and Schiff base of Dapsone with Pyridine-2-carboxaldehye.

 

 

Author Biographies

  • Monika

    Research Scholar, Department of Chemistry, Baba Mastnath University, Rohtak-124021, Haryana, India

  • Arpna

    Assistant Professor, Department of Chemistry, Baba Mastnath University, Rohtak-124021, Haryana, India

  • Pallavi Bhardwaj

    Professor, Department of Chemistry, Baba Mastnath University, Asthal Bohar, Rohtak-124021 , Haryana, India

Published

2024-12-12

Issue

Vol. 28 No. 1 (2025)

Section

Research Article

License

Copyright (c) 2024 Monika, Arpna, Pallavi Bhardwaj (Author)

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

Schiff Base Metal Chloride Complexes of Dapsone and Pyridine-2-Carboxaldehyde Their Synthesis, Characterization And Antifungal Properties. (2024). African Journal of Biomedical Research, 28(1), 09-13. https://doi.org/10.53555/AJBR.v28i1.4875